Chicago museums are presenting a diverse slate of fall 2025 exhibitions, including a major Yoko Ono retrospective at the Museum of Contemporary Art Chicago, the National Museum of Mexican Art's 39th annual Día de Muertos exhibit, a landmark Elizabeth Catlett retrospective at the Art Institute of Chicago, a Marvel's Spider-Man interactive show at the Griffin Museum of Science & Industry, and Italian artist Diego Marcon's U.S. debut at The Renaissance Society.
This guide highlights the breadth of Chicago's cultural offerings, from conceptual and political art to community-based memorials and pop-culture spectacles. The exhibitions underscore the city's role as a major art destination, with the Yoko Ono show being the only U.S. stop for that retrospective and the Elizabeth Catlett exhibition providing a timely reexamination of a historically significant activist artist.